Supplementary Material: Transcriptional delay stabilizes bistable gene networks
نویسندگان
چکیده
Chinmaya Gupta, José Manuel López, William Ott, Krešimir Josić, 2 and Matthew R. Bennett 4, 5 Department of Mathematics, University of Houston, Houston, TX Department of Biology & Biochemistry, University of Houston, Houston, TX Department of Biochemistry & Cell Biology, Rice University, Houston, TX Institute of Biosciences & Bioengineering, Rice University, Houston, TX To whom correspondence should be addressed: [email protected]
منابع مشابه
Transcriptional delay stabilizes bistable gene networks.
Transcriptional delay can significantly impact the dynamics of gene networks. Here we examine how such delay affects bistable systems. We investigate several stochastic models of bistable gene networks and find that increasing delay dramatically increases the mean residence times near stable states. To explain this, we introduce a non-Markovian, analytically tractable reduced model. The model s...
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Fig. S1 in the supplementary material accompanying this paper was published incorrectly when the paper first appeared on-line. This has now been rectified and we apologise to the authors and to readers for this mistake.
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تاریخ انتشار 2013